Head-to-head comparison

Makani Science vs. Masimo: Comparing Respiratory Monitoring Solutions

A side-by-side look at the first wireless breathing patch versus the industry standard in acoustic monitoring.

Written by Hustlin from public information. Makani Science hasn’t joined Hustlin.

Makani Science and Masimo both address the critical need for non-invasive patient monitoring, but their technical approaches differ. Makani Science focuses on a wireless patch that captures unique breathing waveforms for predictive analysis, while Masimo is an established global leader offering a broad suite of acoustic and pulse oximetry solutions for hospital environments.

Where Makani Science is strong

  • Wireless patch form factor for continuous, unobtrusive monitoring
  • Captures unique respiratory waveforms for a first-of-its-kind database
  • Founded by UC Irvine experts in wearable sensor technology
  • Focused on predictive machine learning for respiratory complications

Where Masimo is strong

  • Global market leader with extensive clinical validation
  • Broad product ecosystem including acoustic monitoring and pulse oximetry
  • Deep integration with existing hospital monitoring infrastructure

Side-by-side comparison

CategoryMakani ScienceMasimoEdge
Form FactorWireless patchAcoustic sensors/Wired optionsStronger
Primary DataRespiratory waveformsAcoustic signals & SpO2Neck-and-neck
Market StatusFDA clearance expected <1yrEstablished global presenceStronger
Core TechnologyWearable patch + ML databaseAcoustic & Signal ProcessingNeck-and-neck
Beachhead MarketSedation monitoringGeneral hospital/Critical careNeck-and-neck
Data StrategyPredictive disease databaseReal-time clinical vitalsStronger

Which one should you pick?

Pick Makani Science when…

Choose Makani Science if you need a wireless, low-profile solution for continuous breathing monitoring and want to leverage unique respiratory waveform data for predictive insights.

Pick Masimo when…

Choose Masimo if you require a proven, multi-parameter monitoring system that is already integrated into the global healthcare supply chain and hospital workflows.

Frequently asked questions

Is Makani Science better than Masimo?

It depends on the use case. Makani Science offers a more specialized, wireless patch for breathing waveforms, whereas Masimo is better for comprehensive, multi-vital monitoring in traditional clinical settings.

How is Makani Science different from Masimo?

Makani Science uses a wireless patch to collect specific respiratory patterns to build a predictive database. Masimo primarily uses acoustic sensors and pulse oximetry for real-time monitoring.

When should I use Makani Science over Masimo?

Use Makani Science when patient mobility and the collection of unique breathing waveforms are priorities, particularly in sedation environments where a patch is less intrusive.

Does Makani Science have FDA clearance?

Makani Science is currently in the launch stage and expects to receive FDA clearance for its beachhead market within the next year.

What is the long-term goal of Makani Science compared to Masimo?

While Masimo continues to lead in hardware-based monitoring, Makani Science aims to combine its waveform database with machine learning to predict respiratory complications before they occur.

Monitor Breathing with Precision

Learn more about how Makani Science is changing respiratory monitoring with wireless patch technology.

Visit Makani Science

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